The extracellular matrix (ECM) is a dynamic structure that is constantly remodelled to control tissue homeostasis. The ECM in mammals is composed of around 300 proteins, known as the core matrisome.
Researchers suggest targeting ECM-mediated regulation of autophagy levels could be used to sensitize pancreatic cancer to FDA-approved therapies.
The CNS is characterized by a functional network of neurons and glia. It also contains an extracellular matrix (ECM), which has garnered less attention than the cellular component of the CNS despite ...
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