It is known that there are close relationships between bone destruction and tumor growth in bone metastasis. RANKL is a central factor in bone metastasis, inducing osteoclastogenesis mediated by its ...
A comprehensive analytical characterization shows the newly approved denosumab biosimilar SB16 is highly similar to Prolia ...
Researchers have revealed that RANKL expressed by osteocytes is essential for the bone remodeling during orthodontic tooth movement. This result can facilitate the development of novel therapeutic ...
A potential new therapeutic option for the treatment of nonmuscle invasive bladder cancer: Combination of intravesical oncotherad immunotherapy and platelet rich plasma (PRP). This is an ASCO Meeting ...
The authors have no relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials discussed in ...
During orthodontic tooth movement, osteoclastic bone resorption is essential for alveolar bone remodeling. It is well known that the differentiation of osteoclasts is regulated by RANKL. However, the ...
Tokyo Medical and Dental University(TMDU) research team demonstrated that osteocytes have a crucial role in orthodontic tooth movement as the major source of receptor activator of nuclear factor-κB ...