Driving RNA vaccine innovation through microbiome insights is an emerging frontier that moves beyond pathogen-only thinking and toward vaccines designed ...

BackgroundThe emergence of the first biopolymers and their building blocks on the early Earth is considered a key moment in the origin of life (OoL ...

Two separate laboratory breakthroughs have produced RNA molecules that can build copies of themselves or assemble functional structures without any help from proteins or DNA. These results offer the ...

A strand of RNA just 45 nucleotides long has been discovered to perform two key reactions required for self-replication. The ...

The eukaryotic spliceosome is a multi-megadalton ribonucleoprotein (RNP) complex found in eukaryotic nuclei that catalyzes the removal of introns (non-coding regions) from pre-mRNA and splices exons ...

A 45-nucleotide strand of RNA can now synthesize both its mirror-image complement and a copy of itself, bringing scientists ...

One of the greatest mysteries of our planet is how a soup of lifeless chemicals transformed into the first living cell. There are several competing theories about where this happened, from frozen ...

Previously discovered large RNA polymerase ribozyme structure (grey, based on pdb: 8T2P) vs. newly discovered small RNA polymerase ribozyme QT45 (blue, AlphaFold3 prediction). Credit: MRC Laboratory ...

Life may have begun when RNA molecules began to replicate themselves, and now we’ve finally found an RNA molecule that is very close to being able to do this ...

Hidden inside the human body, scientists have uncovered thousands of bizarre RNA loops unlike anything in biology. These microscopic structures don’t act like viruses or bacteria and could rewrite ...

Researchers from Carnegie Mellon University have discovered a way to target RNA that could lead to new treatment options for myotonic dystrophy type 1 (DM1), the most common adult-onset form of ...